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Fenbendazole is a benzimidazole anthelmintic (deworming) medicine used in veterinary medicine for animals such as dogs, cattle, and horses. In recent years, it has gained attention as a potential cancer treatment due to preclinical studies (in labs and animals) and anecdotal reports of success in humans. However, it is not approved for human use by the FDA or other regulatory agencies.
Studies attribute the anti-cancer mechanisms of fenbendazole to increasing p53 activation, inhibiting the GLUT1 transporter and hexokinase, and reducing glucose uptake in cancer cells.
Disclaimer: This information is for educational purposes only and does not constitute medical advice. Always consult a qualified healthcare provider for any questions regarding a medical condition or treatment.
Cancer metabolic reprogramming: importance, main features, and potentials for precise targeted anti-cancer therapies. Cancer Biol Med 11(1): 1-19, 2014. DOI: 10.7497/j.issn.2095-3941.2014.01.001
Fenbendazole is a benzimidazole anthelmintic (deworming) medicine used in veterinary medicine for animals such as dogs, cattle, and horses. In recent years, it has gained attention as a potential cancer treatment due to preclinical studies (in labs and animals) and anecdotal reports of success in humans. However, it is not approved for human use by the FDA or other regulatory agencies.
Studies attribute the anti-cancer mechanisms of fenbendazole to increasing p53 activation, inhibiting the GLUT1 transporter and hexokinase, and reducing glucose uptake in cancer cells.
Disclaimer: This information is for educational purposes only and does not constitute medical advice. Always consult a qualified healthcare provider for any questions regarding a medical condition or treatment.
Cancer metabolic reprogramming: importance, main features, and potentials for precise targeted anti-cancer therapies. Cancer Biol Med 11(1): 1-19, 2014. DOI: 10.7497/j.issn.2095-3941.2014.01.001